edta and glutathione Chelation Therapy & Detoxification The Glutathione System: A Journey

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Design of such a trial should be given some consideration because the goals here are multiple: first to determine how long the effect would last, second to determine effectiveness of a repeat treatment, and third the general health of the patient and how well they tolerate the repeat treatments

Besides, an inherent limitation in the cross-sectional design is the inability to infer causality

Although the high CL/F strongly indicates it has a low systemic availability, we cannot fully understand root cause, e.g., poor membrane permeability, low aqueous solubility, high first pass metabolism in gut wall and liver, etc

The matter with glutathione is straightforward to explain