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MMP, a key indicator of mitochondrial functionality, was assessed using JC-1 dye, which differentiates between energized and depolarized mitochondria

However, the review emphasized that the majority of studies utilized small rodent models, and efficacy in humans remains to be confirmed through adequately powered clinical trials

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However, experts recommend getting your vitamin B12 from food, before trying a supplement

3 Gut microbiota-ENS crosstalk in colitis pathogenesis 3.1 Bidirectional signaling between microbial communities and ENS function The ENS operates as a dynamic integrative hub enabling continuous bidirectional communication between the gut microbiota and the CNS, thereby coordinating neural, immune, and metabolic responses