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PKC delta (PRKCD) is required for fear learning in lateral amygdala (Yu et al., 2017) and GABAergic neurons highly express PRKCD on alcohol exposure (Hongpaisan et al., 2011), mediates response to allosteric GABA-A receptors (Hodge et al., 2002), has a role in a recognition memory task (Zisopoulou et al., 2013), may mediate seizure mechanisms (Toth, 2005), mediates the neuroprotective effect of estrogen (Jung et al., 2005) and is significantly suppressed in hipoocampal CA1 in a Fragile X syndrome mouse model (Marsillo et al., 2021)

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