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Guidelines for diagnosis and treatment of acute pancreatitis in China (2021)

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16,326 In conditions of nutrient excess, as seen in T2DM, insulin resistance blunts insulin-mediated nutrient and energy responses, impairing nerve metabolism and bioenergetic failure

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Causes and Risk Factors of Peripheral Neuropathy The nerve damage behind neuropathy can happen in a variety of ways, affecting the nerve axons (along which impulses transmit to other cells), myelin sheath (which covers and protects the axon), or a combination of both