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Inhibition of D1, D2, and A-cyclin expression in HL-60 cells by the lipid peroxydation product 4-hydroxynonenal

Oxidoreductases including dehydrogenases, oxygenases, oxidases, and peroxidases comprise a large family of enzymes responsible for redox reactions in central carbon metabolism 16

GPS has been shown to mitigate lipid peroxidation by enhancing the activity of key antioxidant enzymes, including superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px)

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Meta-analysis further showed that striatal and thalamic serotonin transporters, along with cortical serotonin 2A (5-HT2A) receptors, show greater age-related decreases than raphe nucleus serotonin 1A (5-HT1A) receptors [76]