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Therefore, blocking the HMGB1-AGER pathway with small molecules or genetic methods could limit the inflammatory response mediated by ferroptosis ( Radiotherapy Radiotherapy can directly cause oxidative damage to lipid membrane, leading to the accumulation of toxic lipid peroxidation and triggering ferroptosis in cancer cells

ex vivo ), the muscle preparation (isolated or intact), the primary fiber type utilized, and other factors (Figure 2)

Chronic low-grade inflammation, often referred to as inflammaging, has been associated with alterations in the ovarian microenvironment, potentially affecting follicular development and oocyte maturation [67]

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Phosphorylated tau-217 in blood has shown promising accuracy in detecting AD pathology 9