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This shift in metabolic capacity of synovial cells enables them to produce the essential building blocks to support their proliferation, activation and invasiveness

10.1093/oxfordjournals.bmb.a073628 56 HeislerS.ReisineT

Contamination from repeated dropper contact introduces proteolytic enzymes that cleave peptide bondssterile technique and single-use aliquots prevent bacterial degradation independent of temperature control