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During early sepsis, ATF3 alleviates hyperinflammation and promotes tissue recovery, whereas its sustained overexpression contributes to late-phase immunosuppression and secondary infections (142,161,162,187)

Transgenic Arabidopsis thaliana plants expressing bacterial -hexachlorocyclohexane dehydrochlorinase LinA

However, when ROS levels increase, they can become harmful, leading to oxidative stress and disease

DOI:10.1016/j.coi.2019.05.006 19

BELN supplementation also improves liver dysfunction and insulin resistance in NAFLD, which is accompanied by a reduction in AST and ALT levels and fat deposition as well as a downregulation in acetyl-CoA carboxylase 1 (ACC1) and fatty acid synthase (FAS) expression (252)