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Some of the first symptoms of a metabolic crisis are: extreme sleepiness behavior changes irritable mood poor appetite Other symptoms then follow: fever nausea diarrhea vomiting hypoglycemia If a metabolic crisis is not treated, a child with CTD can develop: breathing problems swelling of the brain seizuresThese are also called "convulsions" or "fits." During a seizure, a person loses consciousness and control of his or her muscles

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GLP-1/GIP therapy (Tirzepatide) activates both GLP-1 and GIP receptors often delivering stronger appetite control and metabolic benefits

3.6 The three-dimensional crystal structure of MSA-DH To further investigate the molecular mechanism and cofactor utilization of MSA-DH, the X-ray protein structure was determined at 2.6 (data collection and refinement statistics in Supplementary Table S1)

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