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Additionally, polymorphisms in the AKR1B1 gene, which encodes aldose reductase and is involved in the metabolic pathways of diabetic complications, are significantly associated with the risk of retinopathy in diabetic patients

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In this Review, we highlight the latest advances in our understanding of the mechanisms of action of metformin and discuss potential emerging novel therapeutic uses

It is an eating plan where you eat meals that are high in fat and protein, and low in carbohydrates