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These genes play a crucial role in the development, signal transduction, and synaptogenesis of GABAergic neurons, and their aberrant expression or dysfunction is closely linked to the pathogenesis of ASD

49,125,126 In addition to ameliorating the central manifestations of cocaine intoxication, benzodiazepines decrease the centrally-mediated and peripheral sympathomimetic outflow that contributes to the symptoms of cocaine-associated chest pain

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Defects in cellular ATP production found in several regions of PD brains have been associated with mitochondrial dysfunction 71 , and previous studies showing that HPRT1 deficiency inhibits mitochondrial protein complex I-dependent respiration 72 indicate that HPRT1 may be involved in energy metabolism dysregulations in PD

"Childhood Health and Educational Outcomes Associated With Maternal Sleep Apnea: A Population Record-Linkage Study"