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Liu, C., N

Environmental contaminants, including particulate matter, ozone, and nitrogen oxides, amplify oxidative stress and inflammatory responses, further accelerating lung tissue damage and the development of respiratory conditions

As an example, GSH depletion has been shown to promote pro-inflammatory microglial phenotypes and amplify astrocyte-microglia crosstalk (Vilhardt et al., 2017)

Dendritic distribution of CDK5 mRNA and p35 mRNA, and a glutamate-responsive increase of CDK5/p25 complex contribute to tau hyperphosphorylation