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Early preclinical data showed a prolonged life span and delay in decline in motor performance with preservation of motor neurons in the lumbar spinal cord of SOD1 mouse models [162]

Wyss, V., Ganzit, G

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241,242 However, the study did not observe an increase in Bacteroidetes and a reduction in Firmicutes, as reported in both R6/1 and R6/2 mice