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Furthermore, non-coding RNAs are implicated in chronic low-grade systemic inflammation, known as inflammageing, impacting the energetic, oxidative and inflammatory status of senescent cells by modulating NF-B/NLR family pyrin domain containing 3 (NLRP3) pathways and triggering senescence-associated secretory phenotype (43)

demonstrated that the depletion or inhibition of arginine did not influence M

Notably, compared with the control group (baseline: 89.8% of parasites expressing iron utilization-related genes among all parasites), the proportion of parasites expressing these genes increased to 96.1% after 3 h of DHA treatment and 96.0% after 9 h of DHA treatment

Therefore, targeting cellular oxidative stress, i.e., inhibiting lipid peroxidation, could be a way to inhibit ferroptosis

Statins Statins are lipid-lowering drugs that prevent cholesterol synthesis by inhibiting 3-hydroxy-3-methylglutaryl-CoA reductase, commonly used in treating hypercholesterolemia and cardiovascular-related diseases [151]