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Emphasize safety, especially thiol-reactivityrelated off-target risks (Lu, 2024

Furthermore, 4-HNE is documented to possess a reactive preference towards amino and thiol groups (1, 39, 40)

Effect of Aging on NAD+ Levels NAD+ Biosynthetic Pathways Decline With Age The decline in NAD+ biosynthetic pathways in the course of aging could be a possible explanation for the reduction of NAD+ levels