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[33] In chronic inflammatory bowel diseases, including Crohns disease, systematic reviews (including Cochrane reviews) have concluded that current randomized evidence is insufficient to support glutamine supplementation for inducing remission or modifying disease progression, and further well-powered clinical trials are required

105111, 2018 [40] M

FDA has raised regulatory and safety concerns regarding certain BPC-157-related bulk substances used in compounding contexts, and the dietary supplement classification of BPC-157 products has been a topic of industry discussion through 2025 and into 2026