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The stakes are simply too high to accept theoretical risk

Archived from the original on 3 July 2021

Dr Peter Tyrer suggests the following manoeuvre when a severe withdrawal symptom such as a panic attack comes on when you are pushing a trolley round a supermarket: Take much slower and deeper breaths, making sure that you get air deep down into the lungs instead of just at the top of the chest. As you do this you will find that your arms and hands relax so that the whites of your knuckles no longer show as you grip the supermarket trolley. Do not move on until you feel the tension flowing out of your hands

There is no established dose equivalence table between these compounds because they have different receptor profiles and potencies

Levels rose to record highs on Tuesday