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Results of a recent study in MM patients, evaluated according to the International Staging System (ISS) (56, 57), revealed that ADO levels in BM plasma samples at diagnosis were higher in patients at an advanced stage (ISS = III) with symptomatic MM than in those at the earlier MGUS/SMM stages (pooled ISS = I-II) (58)

Proper hydration and rest are usually all that is needed for a full recovery

When uncertain, query the provider

[1] This discomfort is usually transient and can be minimized by using proper technique and allowing the solution to come to room temperature before injection

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