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Further molecular mechanism by which L-carnitine reduces inflammation involves the induction of peroxisome proliferator-activated receptor- (PPAR-), a receptor that suppresses the expression of inflammatory genes and promotes the resolution of inflammation [9]

[DOI] [PubMed] [Google Scholar] Meyerhardt JA, et al

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L-arginine is generally safe, but it may not be right for people with certain health conditions like recent heart attack, low blood pressure, asthma, or herpes

Spreading depression triggers headache by activating neuronal panx1 channels