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KU Leuven) T_04 GOVERNANCE (A): Learning and institutions A1-11 (YTU Davutpasa Campus) A1-11 YTU Davutpasa Campus Convener: Raine Mantysalo (Aalto University) 245 City-to-City Learning for a Climate-Neutral Future: Insights from the NetZeroCities Twinning Learning Programme With cities facing complex and systemic challenges, city-to-city (C2C) collaborations are increasingly recognised as an effective mechanism for municipal capacity building and transfer of knowledge and practices (Moodley, 2020)

76 Familial AD (FAD) is predominantly characterized by autosomal dominant genetic mutations in amyloid precursor protein (APP), presenilin 1 (PS1), and presenilin 2 (PS2) genes, typically manifesting between 30-65 years and progressing rapidly

Beyond these established agents, topical amitriptyline has recently shown promising real-world effectiveness with acceptable tolerability in observational cohorts, yet rigorous randomized evaluations remain warranted to define effect size, optimal formulation, and durability 19

Increasing evidence highlights natural polysaccharides as promising therapeutic agents due to their dual roles in microbiota modulation and barrier reinforcement

There is no single right age to start