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IQC material should be used at concentrations which provide a clinically relevant challenge to the assay

Mercaptopropionylglycine showed protective activity against cardiac reperfusion/ischemia injury ( Amifostine is hydrolyzed in vivo to WR-1065, which is also clinically used during radiotherapy as a protectant (WR stands for Walter Reed Army Hospital where this compound, and many other of the WR series, were developed) (Nair et al., 2001)

ER-mitochondria tethering by PDZD8 regulates Ca2+ dynamics in mammalian neurons

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These include nausea, dizziness, muscle cramping, diarrhoea, dehydration, weight gain, bloating, heat intolerance, and gastrointestinal pain [8, 4, 9, 10]