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[148] found that the overall positive charge of SP 1828 , which is more positively charged by the removal of E29, combined with the extended hydrophobic interface, resulted in a higher intracellular uptake rate of the peptide compared to its longer corresponding peptide SP 1831 , indicating that positive NC seems to have the ability to enhance cell uptake and biological activity

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The involvement of heme oxygenase-1 activity in the therapeutic actions of 5-aminosalicylic acid in rat colitis