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The primary difference is duration and effect: IGF-1 LR3 lasts 2030 hours and works systemically across the body

J., Liu, X., Saunders, M

The Journal of Physiology, 593 (18), 4285-4301

J Interferon Cytokine Res (2013) 33:2709

Collectively, these observations establish that the functional impact of ammonia on tumor progression and immune modulation cannot be generalized without considering spatial and anatomical context