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10.1001/jama.2011.1437 JAMA 83 KnowlesR

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doi: 10.1038/s41556-024-01507-7 55 YangMWeiXYiXJiangD-S

For other products, long-term exposure to cold temperatures can shorten the products lifespan, negatively impact stability and affect performance

Need for research on more long-term biomarker (e.g

N-acetylcysteine (NAC) Provides cysteine (rate-limiting amino acid) Shown to increase glutathione levels Widely studied in oxidative stress, respiratory health, and liver support