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C., Sturley, S

doi: 10.1111/j.1600-065X.2008.00628.x 31 ManhartNVierlingerKSpittlerABergmeisterHSautnerTRothE

The Journal of Clinical Psychiatry

Bottom line: Intermittent use (2-3x weekly) generally doesnt need cycling

Notably, Erastin-induced GSH depletion also promotes cardiolipin peroxidation, which not only triggers the opening of the mitochondrial permeability transition pore but also induces caspase-dependent and -independent apoptosis [218, 220,221,222]