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Cellular stress induced by either stress or SUD plays a significant role in this process, offering potential therapeutic targets

GEN (120 mg/kg bwt in 1 mL saline) was administered i.p

Imaging 34, 377383

4 Mitochondrial DNA: a key player and victim in HIV pathogenesis Mitochondrial DNA (mtDNA) occupies a dual role in HIV pathogenesis: it is both a target for viral-induced damage and a potent activator of innate immune pathways that drive chronic inflammation