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PDKs act as metabolic gatekeepers by inhibiting the pyruvate dehydrogenase complex (PDHC), diverting glucose flux away from mitochondrial oxidation toward glycolysis

Moreover, ribosome biogenesis is required for mRNA translation, placing pre-rRNA synthesis at the origin of the most energy-demanding cellular activities 4,6

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Arsenic is eliminated from the body in a couple of steps: metabolized (broken down) into methylarsonic acid and dimethylarsinic acid then excreted in the urine Getting a little more in-depth: The process of metabolizing arsenic so that it can be excreted in the urine involves methylation and redox reactions