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Somatic mutation of the NRF2 pathway genes plays a role in some human cancers (235, 236)

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[54] In HepG2 cell lines, eugenol protects human liver HepG2 cells from H 2 O 2 -induced oxidative hepatotoxicity by maintaining ROS homeostasis, increasing IL-10 levels, and upregulating cytochrome gene expression

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Faulder CG, Hirrell PA, Hume R, Strange RC

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2017 May 16;474(11):1823-1836

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But they're usually not the first medicine your doctor will try because, in most cases, TNF inhibitors and interleukin inhibitors work the best

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