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When LPS interacts with host immune cells, it is carried to Toll-like receptor 4 (TLR4) and its coreceptor myeloid differentiation factor 2 (MD2) via LPS-binding protein (LBP) and CD14 (cluster-differentiation 14), and the host immune system then recognizes the contact made by LPS (Tsukamoto et al

In SERS and SPRS, noble metal nanomaterials like gold and silver NPs amplify Raman or optical signals through LSPR, enabling single-molecule detection and highly specific recognition of biological markers

Four-year clinical update and treatment switching-adjusted outcomes with first-line nivolumab plus ipilimumab with chemotherapy for metastatic non-small cell lung cancer in the CheckMate 9LA randomized trial

Available from: Eisenga MF, Minovi I, Berger SP, Kootstra-Ros JE, van den Berg E, Riphagen IJ et al

After this, it was thawed on ice and vortexed for 2 min