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Health effects of red wine consumption: a narrative review of an issue that still deserves debate

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In fact, the caspase-mediated cleavage of PARP into 89- and 24-kDa fragments inactivates the enzyme by destroying its ability to respond to DNA strand breaks, thereby preventing the loss of cellular ATP associated with PARP activation and thereby allowing the maintenance of the cellular energy essential for the execution of apoptosis

HEK293T cells were transiently transfected with PLG3-Basis-T-bet promoter and pRL-TK vector, and then treated with PBS or d-serine (10 mM, Sigma) (purity 98%) for 48 h

Although many natural products have been found to induce ferroptosis in tumor cells, however, further research is needed to discover and study the molecular mechanisms and clinical efficacy of these natural products