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Serum creatinine, lipid concentrations, and other routine laboratory parameters were assessed by a Beckman Coulter Synchron CX9 automatic analyzer whereas glycosylated hemoglobin (HbA 1c ) was evaluated by high-performance liquid chromatography [normal laboratory range, 25.0 mmol/mol to 38.9 mmol/mol (International Federation of Clinical Chemistry and Laboratory Medicine) or 4.4% to 5.7% (Diabetes Control and Complications Trial)

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However, the inverse association between adherence to MD and decrease in liver fat content might be largely mediated (i.e., driven) by a decrease in BMI [74] emphasizing the central role of adipose tissue-liver crosstalk when studying liver-related outcomes [79]

(2019) demonstrated that serum levels of TMAO are positively correlated with the serum levels of total BA in patients with MAFLD by conducting a case-control study, and administration of TMAO impairs liver function and increases hepatic triglyceride accumulation and lipogenesis in a murine model