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When AGE-RAGE binding occurs, a signaling cascade activates proteins and kinases which eventually converge on IB, whose phosphorylation results in degradations allowing translocation of NF-B from the cytoplasm to the nucleus promoting transcription of pro-inflammatory genes (7375)

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Glutathione is normally produced by the body in response to todays environment such as pollution from the air we breathe, the water we drink, chemicals and pesticides in the food we eat that causes damages in our cells and circulatory system

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