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In addition, receptors for AGEs can be stimulated by non-glycated compounds such as S100/calgranulins isoforms , -amyloid, amphoterin, advanced oxidation protein products, and ligands implicated in vascular injury

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Mizoguchi et al .[] and Papanikolaou et al .[] observed that Salmonella typhimurium and Salmonella dublin -induced colitis on mice shows inflammation similar to histopathological characteristics to human UC, including epithelial crypt loss, erosion, and neutrophil inflltration

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For instance, anabolism consumes energy in the form of ATP or NADH to synthesize biomolecules such as DNA and proteins, while catabolic reactions break down macromolecules, releasing energy in the form of ATP or NADH, which can be reutilized to generate NAD + 2