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[PubMed: 9309699] 265

Neurol 77, 146153 (2015)

Haroon HB, Mukherjee D, Anbu J, Teja BV

Growth hormone antibodies formation in patients treated with recombinant human growth hormone

Based on the copper content measurements, all recombinantly produced proteins ( jr PPO1-wt and five mutants) contain a similar amount of copper (~0.81.1 copper ions per protein), indicating that the changes in activity are not based on the number of copper ions in the active center