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Disruptions in glucose homeostasis caused by p53 increase circulating glucose levels, which is a characteristic of type 2 diabetes (T2D)

Chemical structures have been accurately depicted using ChemDraw software (ver 12.0.2

Unprocessed and processed (with the protein ladder) western blot images for Fig

In vivo and in vitro experiments have shown that by intervening related enzymes or downstream metabolites to interfere with methionine metabolism, the liver injuries could be reduced