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The SOX4/EZH2/SLC7A11 signaling axis mediates ferroptosis in calcium oxalate crystal deposition-induced kidney injury

Nat Genet (2010) 42(7):5705

Ferroptosis is a form of iron- and lipid-peroxide-mediated cell death

It helps lighten skin pigmentation and enhances overall radiance

Long-term fasting in humans has also been shown to induce a reductive shift in the blood acetoacetate/beta-hydroxybutyrate, indicative of the mitochondrial [NAD + ]/[NADH], representing a summed systemic redox change