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This conclusion was challenged when pretreatment with the neutropenia-inducing antibody Gr1 resulted in reduced liver injury [116]

Firstly, long-term exposure to air pollutants (PM2.5, NO, ozone) increases intestinal permeability, systemic inflammation, and dysbiosis [221], The UK Biobank cohort has confirmed that PM2.5 and NO significantly increase the risk of UC [222], Other studies have also revealed a correlation between PM2.5 exposure and increased rates of intestinal resection and mortality [223]

doi: 10.1016/j.gene.2015.12.061 140 HayhoeR

These cells inhibit ferroptosis, creating a protective microenvironment

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