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Amary et al., 2011), leading to a hypermethylation phenotype and may alter the differentiation of cancer stem cells (Yang et al., 2012

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Additionally, it can lead to cause atrophy of the intestinal mucosa, ulceration, and symptoms of enteritis, including abdominal pain and diarrhea [18]

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As one of the most extensively studied cytoprotective peptides, it has a deep preclinical literature spanning tissue repair, gastrointestinal protection, angiogenesis, and the nitric oxide system