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Notably, the concentration profile of these nucleoside components exhibits significant variation depending on the extraction methodology employed, with different decoction techniques resulting in markedly distinct nucleoside compositions in the final extract (Tian et al., 2013)

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between 5 and 10 mM, and comprises ~1015% of the total cellular glutathione in the liver (Jocelyn and Kamminga, 1974) and ~30% in the kidney (Schnellmann, 1991)

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showed that the miR375 targets mRNA of the ADIPOQ receptor ( AdipoR2 ) in hepatocytes, reducing its expression and blunting ADIPOQ-mediated anti-inflammatory signaling