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Description

[5] [6] This effect appears to be dose-dependent and duration-dependent, meaning higher doses and longer treatment periods increase the risk of deficiency

doi: 10.1186/s41232-021-00170-x

Toxicol Lett 1998, 102103: 271275

The authors found that these genes were usually unmethylated in both normal and malignant embryonic cells, but noted that most of these genes occurred within a subset (10% of all genes) associated with PcG in stem cells