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50 ZhangH.WangY.HeZ

10.1371/journal.pone.0154800 202

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Experimental models have shown that T-cells express a vitamin D receptor, and that lack of vitamin D signaling causes T-cells to produce higher levels of inflammatory cytokines

In this sense, gut microbiota signifies a field of growing interest in the understanding of several processes in the organism regulating a plethora of metabolic routes, having a very close interplay with the immune system [60]