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Description

Mitochondrial dysfunction induces senescence with a distinct secretory phenotype

Bologa, C., Lionte, C., Popescu, A., Sorodoc, V., & Sorodoc, L

Thus, by regulating M1 macrophage activity, the anti-M1 agent directly reduces inflammation and tissue damage, and indirectly prevents the profibrotic activation of M2 macrophages 27