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[53] Oxidative stress also contributes to tissue injury following irradiation and hyperoxia, as well as in diabetes

Targeting specific molecular pathways in reactive astrocytes presents additional therapeutic opportunities

10.2.1 Disulfiram in combination with temozolomide The 5-year survival rate of patients with GBM treated with radiation alone was 1.9%, and TMZ, in conjunction with radiation therapy, only increased the rate to 9.8% (Triscott et al., 2015)