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Description

The mixture was poured into H 2 O, then the mixture was extracted with EtOAc (3), the combined organic layers were washed with brine, dried over Na 2 SO 4 , then filtered and concentrated under reduced pressure

doi:10.1093/ageing/afg109

Muppidi JR, Arnon TI, Bronevetsky Y, Veerapen N, Tanaka M, Besra GS, Cyster JG

Journal of the Chinese Medical Association : JCMA

These cytokines not only amplify local inflammation but also further disrupt the System Xc GSHGPX4 axis and upregulate ACSL4 in neighboring tubular cells, creating a ferroptosis-inflammatory cascade that expands tubular injury