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Description

Biomedicine & Pharmacotherapy , 161 , 114460

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This treatment is very effective and can provide long term relief

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MMP-9 produced by neutrophils disrupts the integrity of the BBB effectively exacerbating pathologic neuroinflammation

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NAC was demonstrated to have a significant effect on neurocognition (processing speed) but not on negative symptoms

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Additionally, the inhibition of LRRK2 has been linked to reduced ferroptotic damage via the p62/Keap1/NRF2 axis (132) and teneligliptin, a dipeptidyl peptidase-4 inhibitor, decreases ROS levels and prevents ferroptosis (133)

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