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The considerable TSB of SBS-PolkKO mutations suggests that the endogenous lesions driving mutation in the absence of Pol are also repaired by a transcription-coupled mechanism

Common side effects include gastrointestinal symptoms like nausea, vomiting, and diarrhea

As genetic variants are determined at conception they are much less affected by the confounders that can bias conventional observational studies, such as socioeconomic position, so MR studies minimize confounding

They actively support neurological health, improve emotional resilience, and enhance cognitive performancemaking them a valuable tool for anyone seeking better mental balance, sharper focus, and improved quality of life

Available at: Nature Ishida J, Saitoh M, Ebner N, et al