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doi:10.1016/j.freeradbiomed.2014.07.019

In the LPS-induced acutelung injury mouse model, treatment of GHK-Cu also significantly suppressed TNF- and IL-6 expression with a significant decrease of both NF-B p65 and p38 MAPK signaling, suggesting that GHK-Cu is useful for the development of novel anti-inflammatory therapies [22]

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The dividing line between what we call soluble and what we call insoluble is arbitrary, but the following are common criteria for describing substances as insoluble, soluble, or moderately soluble

Chen, J., Li, X., Ge, C., Min, J