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Glutathione (GSH), the brains most prominent intracellular antioxidant, has been suspected to play a key protective role in free-radical-mediated damage to neurons [21], giving rise to the redox dysregulation hypothesis of schizophrenia [22]

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For example, the aryl hydrocarbon receptor plays role in induction of UGT1A1 while the activation of pregnane X receptor and the constitutive androstane receptor leads to induction of UGT1A6 and UGT1A9 (Lin & Wong, 2002, Mackenzie et al., 2003, Xie et al., 2003)

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Hydrogen peroxide (H 2 O 2 ) in the tissue was extracted by extraction buffer made with 1% (W/V) trichloro acetic acid (TCA) solution