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2 Mapping cerebellar circuits: anatomical insights into pain processing 2.1 Cerebrocortical and cerebellar contributions to pain modulation Pain is a multidimensional experience arising from the interplay of sensory, affective, cognitive, and social factors (20), processed through distributed brain networks that include the thalamus, brainstem nuclei, somatosensory cortices, and prefrontal regions (21)

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Naochang Tongtiao acupuncture applied at anterior oblique line of vertex-temporal, Zhongwan (CV12), CV4, Tianshu (ST25), ST36, Shangjuxu (ST37) and Xiajuxu (ST39) can decrease plasma level of TMAO and improve the nerve function in stroke patients (Wang et al., 2022a)

B-12 injections provide several health benefits, particularly for those with a deficiency of this vital nutrient

Heat inactivated serum was included as negative control