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They are generally considered to have fewer side effects and be less dangerous than older-generation antidepressants, such as tricyclic antidepressants, because they specifically target the serotonin transporter, rather than affecting a wide range of neurotransmitters (Wang et al., 2018)

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Undeniably, the contradictory results obtained from these clinical studies may have resulted from differences in adjustments for confounding factors such as the characteristics, specimen type, and study sample size of each observational study

Front Pharmacol 9:920